Yellow Fever vaccination is a requirement and you must have the Yellow fever vaccination certificate from home at least 10 days before arrival in Tanzania. The requirement is not all that strict anymore but it saves time to obtain the vaccination before traveling to Tanzania. Malaria prophylactic drugs should be taken before traveling. Malaria prophylactic drugs should be taken before traveling. These are prescription drugs and you should therefore see your doctor before travelling. Note these pills are supposed to be taken a few days before your safari so allow enough time before booking your doctor appointment. Of course the best way to combat malaria is not to get bitten at all. A repellent with 30% Diethyltoluamide (DEET) worn in the evenings when the malarial anopheles mosquito is active should be effective in preventing bites.
Do not forget your sunscreen as the sun can get very strong during the day.
If you are planning to head to Tanzania from yellow fever infected country, you will need to carry a yellow fever vaccination certificate. However, it's advised to have the yellow fever vaccination before departure which will protect you for 10 years.
Occasionally, dengue fever pops up in Tanzania, particularly in Tanzania's largest and most populous city, Dar Es Salaam. Similar to mosquito-borne malaria, dengue fever causes excruciating muscle-joint pain and throws in a fever for that extra punch. You can get each strain of dengue fever only once, but there are 5 strains.