Tanzania is a vast and wild country with a regulated tourism industry. Unlike some areas of South America, South Africa, and other wild places, tourists cannot go it alone, as a 4x4 vehicle is usually needed, along with park permits, camp permits, lodging reservations, and a guide to avoiding dangers from wild animals.

Tanzania has two rail lines. The Tazara line links Dar es Salaam with New Kapiri Mposhi in Zambia via Mbeya and Tunduma. The central line links Dar es Salaam with Kigoma and Mwanza via Morogoro, Dodoma, and Tabora. Rail is safer, though a slower option of travel.

Express and ordinary buses operate along major long-distance routes. Express buses are slightly more expensive but are more comfortable. Ordinary buses tend to make more stops. Reservations are not always possible, so get to the bus with plenty of time before the scheduled departure. Buses are not permitted to operate at night.